China is a highly prevalent area of hepatitis B virus（HBV） infection, with at least 75 million hepatitis B virus carriers, and 80% of primary hepatocellular carcinoma (HCC) is associated with chronic hepatitis B virus infection. Liver transplantation is currently the preferred method for end-stage liver disease such as biliary atresia and cirrhosis in children. In recent years, children's liver transplantation has developed rapidly and the number of developments has increased significantly. If there is chronic hepatitis B virus infection in the donor liver, it may cause HBV transmission, or the patient may have a low-load occult hepatitis B virus infection, and after immunosuppressive treatment, it may lead to hepatitis B virus infection after surgery.
Study Type
OBSERVATIONAL
Enrollment
100
Chongqing Children's Hospital of Chongqing Medical University
Chongqing, Chongqing Municipality, China
RECRUITINGThe rate of occult hepatitis b virus infection
Clinical follow-up testing for occult HBV infection after liver transplantation in children
Time frame: 3-5 years
The rate of overt hepatitis b virus infection
Clinical follow-up testing for overt HBV infection after liver transplantation in children
Time frame: 3-5 years
The levels and changes of anti-HBs after liver transplantation
Clinical follow-up testing for HBV seromarkers after liver transplantation in children
Time frame: 3-5 years
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