ESBL in Patients Returning to Sweden With Traveller's Diarrhoea

Lund University305 enrolled

Overview

Patients with traveller's diarrhoea frequently harbour Extended Spectrum Betalactamase (ESBL)-producing Enterobacteriaceae (EPE) returning from EPE-endemic areas. This study investigates to what extent travellers returning to Sweden with traveller's diarrhoea carry ESBL in their stool. The isolates are examined further according to species, phenotype, antibiogram and whole genome sequencing.

Samples sent to the department of clinical microbiology in Lund, Sweden for culture of salmonella, shigella, yersinia or campylobacter are also cultured selectively for ESBL. All patients are contacted by mail with the results. ESBL-positive patients are invited to submit further faecal cultures and blood samples during one year follow up time, to investigate how long the patient is colonized with ESBL.

Study Type

OBSERVATIONAL

Enrollment

305

Conditions

Antibiotic Resistant Infection Antibiotic Resistant Strain Traveler's Diarrhea

Interventions

No intervention, observationalOTHER

See above

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * Travellers diarrhoea * foreign traveller Exclusion Criteria: * foreign traveller but no symptoms

Locations (1)

Oskar Ljungquist

Helsingborg, Skåne County, Sweden

Outcomes

Primary Outcomes

Proportion ESBL-colonized after one year.

Defined as a Positive ESBL-culture obtained 12 months after travel

Time frame: 1 year

Data from ClinicalTrials.gov

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