Intra Uterine Growth Restriction

Hospices Civils de Lyon31,052 enrolled

Overview

Intrauterine growth restriction (IUGR) is associated with an increase in perinatal mortality and morbidity, as well as longer-term neurological, cognitive, cardiovascular and endocrine complications. In Europe, about 400,000 pregnancies per year are complicated by IUGR. However, antenatal diagnosis seems insufficient in clinical practice, making it impossible to recognize up to 75% of foetuses with IUGR. At a time when the use of good clinical practice has demonstrated a significant improvement in neonatal survival without severe morbidity, foetuses with IUGR are less likely to receive optimal care. Our hypothesis is that the rate of IUGR diagnosed underestimates the rate of actual IUGR.

Study Type

OBSERVATIONAL

Enrollment

31,052

Conditions

Intrauterine Growth Restriction

Interventions

Intrauterine growth restriction (IUGR)OTHER

Collection of number of patient's diagnosed with IUGR as defined in accordance with the consensus-based definition for early and late IUGR : birthweight \< 3rd centile using French AUDIPOG curves adjusted for term and sex or estimated fetal weight \< 10th centile combined with umbilical artery pulsatility index \> 95th centile or breakage of growth.

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * All birth more than 24 + 0 weeks of amenorrhea at the maternity ward of the hospital Femme-Mère-Enfant * from 1st of january 2011 to 31 december 2017. Exclusion Criteria: * Infants born out of the hospital and secondarily hospitalized in the hospital Femme-Mère-Enfant . * Multiple pregnancies, * children with congenital fetal anomalies * pregnancies without first trimester ultrasound (to date the pregnancy)

Outcomes

Primary Outcomes

Number of patients diagnosed with Intrauterine growth restriction

IUGR was defined in accordance with the consensus-based definition for early and late IUGR : birthweight \< 3rd centile using French AUDIPOG curves adjusted for term and sex or estimated fetal weight \< 10th centile combined with umbilical artery pulsatility index \> 95th centile or breakage of growth.

Time frame: Between 2011 and 2017