Home blood pressure measurement has been reported to be associated with better clinic blood pressure and daytime blood pressure control. However, no study has evaluated the association between home blood pressure measurement and control of 24-hour ambulatory blood pressure in real world practice. The purpose of the present study is to investigate the effect of home blood pressure measurement on the control of ambulatory blood pressure in the real world. The detailed purposes of the present study are (1) to investigate the effects of home blood pressure measurement on the appropriate control of 24-hour ambulatory blood pressure in hypertensive patients treated with antihypertensive drug, (2) to evaluate the effect of home blood pressure measurement on the occurrence of cardiovascular events and target organ damage, (3) to investigate the status and appropriateness of home blood pressure measurement in the real world, and (4) to investigate factors of home blood pressure measurement methods affecting the treatment of hypertension.
Study Type
OBSERVATIONAL
Enrollment
701
Dongguk University Ilsan Hospital
Goyang-si, Gyeonggi-do, South Korea
Difference of 24-hour blood pressure control rate
difference of 24-hour blood pressure control rate between patients who measure and do not measure home blood pressure
Time frame: at baseline and 3 years of follow up
Difference of daytime blood pressure control rate
Difference of daytime blood pressure control rate between patients who measure and do not measure home blood pressure
Time frame: at baseline and 3 years of follow up
Difference of office blood pressure control rate
Difference of office blood pressure control rate between patients who measure and do not measure home blood pressure
Time frame: at baseline and 3 years of follow up
Difference of systolic and diastolic blood pressure (office, 24-hour, daytime, nighttime)
Difference of systolic and diastolic blood pressure (office, 24-hour, daytime, nighttime) between patients who measure and do not measure home blood pressure
Time frame: at baseline and 3 years of follow up
Rate of home blood pressure measurement
Rate of home blood pressure measurement in study population
Time frame: at baseline and 3 years of follow up
Reflection of home blood pressure
Rate of reflecting home blood pressure in the treatment of hypertension at office
Time frame: at baseline and 3 years of follow up
cardiovascular disease prevalence and target organ damage
Difference of cardiovascular disease prevalence and target organ damage between patient who do or do not measure home blood pressure * Composites of cardiovascular disease: number of participants with non-fatal myocardial infarction, angina pectoris, revascularization of arteries, stroke, transient ischemic attack, atrial fibrillation, heart failure hospitalization, progression to end-stage renal failure or elevation of creatinine more than 2-fold, other undefined cardiovascular events at the discretion of the investigator * Target organ damage: left ventricular hypertrophy by electrocardiography, brachial-ankle pulse wave velocity, microalbuminuria
Time frame: at baseline and 3 years of follow up
Changes of home blood pressure measurement rate
Changes of home blood pressure measurement rate in study population after 3 year of follow up from baseline
Time frame: from baseline to 3 years of follow up
Cardiovascular disease events and target organ damage
Difference of occurrence of cardiovascular disease events and target organ damage between patient who measure and do not measure home blood pressure * Composites of cardiovascular disease events: number of participants with first occurrence of non-fatal myocardial infarction, angina pectoris, revascularization of arteries, stroke, transient ischemic attack, atrial fibrillation, heart failure hospitalization, progression to end-stage renal failure or elevation of creatinine more than 2-fold, other undefined cardiovascular events at the discretion of the investigator * Target organ damage: left ventricular hypertrophy by electrocardiography, brachial-ankle pulse wave velocity, microalbuminuria from enrollment
Time frame: during 3 years of follow up from baseline measurement
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