The Glycemic Effect of Added Sugar on Bake Beans

Singapore Institute of Food and Biotechnology Innovation12 enrolled

Overview

To investigate the effect of added sugar to bake beans on glycemic and insulinemic response.

There will be a total of 7 test session. Each session will last for 3 hours. At each test session, volunteers will be served with 7 test meals and blood will be collected. After an overnight fast, subjects will visit the research center. Two fasting capillary blood samples will be collected via fingerpick. Following the fasting samples, volunteers will consume the test meals. Further blood samples will be collected at 15, 30, 45, 60, 90, 120, 150, 180 minutes after the ingestion of test meal. These samples will be used to analyses for whole capillary blood glucose. At every 30 minute interval, samples will be collected for analysis of capillary plasma insulin.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

NONE

Enrollment

Conditions

Diabetes Mellitus, Type 2 Obesity PreDiabetes

Interventions

Glucose Reference 1OTHER

30 g of glucose dissolved in 250 ml of water

Glucose Reference 2OTHER

30 g of glucose dissolved in 250 ml of water

Glucose reference 3OTHER

30 g of glucose dissolved in 250 ml of water

Eligibility

Sex: MALEMin age: 21 YearsMax age: 60 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Chinese ethnicity * Age ≥21 and ≤ 60 years * Body mass index between 18.5 to 25 kg/m2 * Normal blood pressure \<140/90 mmHg * Fasting blood glucose \<6.0 mmol/L * In general good health Exclusion Criteria: * Current Smoker * have any metabolic diseases (such as diabetes, hypertension etc) * have known glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency) * having medical conditions and/or taking medications known to affect glycaemia (glucocorticoids, thyroid hormones, thiazide diuretics) * have intolerances or allergies to any foods * partake in sports at the competitive and/or endurance levels * intentionally restrict food intake

Locations (1)

Clinical Nutrition Research Centre

Singapore, Singapore

Outcomes

Primary Outcomes

Glucose [

Whole capillary blood glucose will be measure using Hemocue analyser

Time frame: Up to 180 minutes

Secondary Outcomes

Insulin

Capillary plasma will be measure using Cobas analyser

Time frame: Up to 180 minutes

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.