The investigators have demonstrated that social software could improve warfarin therapy quality by Human management. however,the efficiency of management will decline if patients' number expands huge. So it is needed that a human-like and automatic management tool could replace the human work. The aim of this study is to evaluate whether an AI-based social software management model could replace human to guide warfarin therapy.
1. The investigators have developed an AI-based miniprogram, and embedded in the Wechat social application. 2. The investigators invited patients receiving warfarin therapy to participant this randomized controlled trial . 3. Participants were randomized to the experimental group and control group in a ratio of 1:1. 4. Participants' warfarin therapy were managed by an AI-based social miniprogram and a Human-based social miniprogram respectively. 5. International normalized ratio(INR) was monitored once a month at least, and the time in therapeutic range was calculated to evaluate the warfarin anticoagulation quality. 6. Participants were followed-up for 24 months, and clinical events, including major bleedings and thrombotic events were recorded during follow-up.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
500
a AI-based miniprogram, embedded in the Wechat social software, to manage participants' warfarin therapy, such as dose adjustment, INR monitoring alert, etc.
a Human-based miniprogram, embedded in the Wechat social software, to manage participants' warfarin therapy, such as dose adjustment, INR monitoring alert, etc.
WAHH
Wuhan, Hubei, China
Wuhan Asia Heart Hospital
Wuhan, Hubei, China
Time in therapeutic range
Calculated Time of international normalized ratio in therapeutic range
Time frame: 24 months
INR variability
coefficient of variation of international normalized ratio (INR)
Time frame: 24 months
Bleeding events
Including Cerebral hemorrhage, gastrointestinal bleeding and other major bleeding
Time frame: 24 months
Thrombotic events
Including stroke, deep vein thrombosis,Pulmonary embolism,Peripheral arterial embolism, et.al
Time frame: 24 months
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.