Thirty patients will be recruited from the outpatient clinic of the faculty of dentistry.fifteen systemically healthy individuals with normal mucosa and fifteen atrophic/erosive oral lichen planus patients. Oral lichen planus patients will be treated with a topical steroid and miR-155 and IL-10 will be assessed in saliva before and after 4 weeks of topical steroids use
Study Type
OBSERVATIONAL
Enrollment
30
treatment of OLP with topical steroid
Faculty of Dentistry
Cairo, Egypt
Measurement of salivary levels of miR-155 in OLP before treatment
assessment of miR-155 in saliva of patients with OLP before treatment
Time frame: baseline
Measurement of salivary levels of IL-10 in OLP before treatment
assessment of IL-10 in saliva of patients with OLP before treatment
Time frame: baseline
Measurement of salivary levels of miR-155 in OLP after treatment
assessment of miR-155 in saliva of patients with OLP after treatment
Time frame: 4 weeks
Measurement of salivary levels of IL-10 in OLP after treatment
assessment of IL-10 in saliva of patients with OLP after treatment
Time frame: 4 weeks
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