A Study to Determine Frequency of DNA-repair Defects in Men With Metastatic Prostate Cancer

Inclusion Criteria: * Diagnosis of metastatic (Stage IV) prostate cancer (PC), confirmed by either biopsy of a metastatic tumor site or history of localized disease supported by metastatic disease on imaging studies (that is \[i.e.\], clearly noted in hospital/clinical records) * Signed Informed consent form (ICF) * No condition for which, in the opinion of the investigator, participation would not be in the best interest of the participant (for example \[e.g.\], compromise the well-being) or that could prevent, limit, or confound the protocol-specified assessments * Willing to provide a saliva, blood, and/or archival tumor tissue sample for genomic analysis * No prior poly (adenosine diphosphate \[ADP\]-ribose) polymerase inhibitor (PARPi) for the treatment of prostate cancer * No prior DNA-repair gene defect test results from a Janssen sponsored interventional trial