To evaluate the polysomnographic performance of an automatic ventilatory mode compared with the gold standard (manual polysomnographic titration) to adjust chronic non-invasive ventilation by means of a randomized cross-over study.
Prospective randomized crossover study in 26 patients with chronic non-invasive ventilation (NIV) criteria, comparing the NIV titration with polysomnography vs an automatic mode of ventilation. It will be compared with clinical parameters of ventilation, blood analysis and inflammation reactants as well as evaluating the patient's comfort after each mode.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
26
Correction of night ventilation through an automatic mode of ventilation with assured volume with pressure support
Correction of night ventilation through a manual titration of non-invasive mechanical ventilation using polysomnography.
Hospital Clinic Barcelona.
Barcelona, Spain
Partial pressure of carbon dioxide (PaCO2)
Measure levels after each polysomnography using arterial blood gases
Time frame: two weeks
Partial pressure of oxygen (PaO2)
Measure levels after each polysomnography using arterial blood gases
Time frame: two weeks
Oxygen saving time below 90% (CT90%)
Assess the polysomnography reduction in CT90% through the night study.
Time frame: one month
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