Preoperative Serum Albumin and Duration of Intraoperative Hypotension on Postoperative Acute Kidney Injury

Peking University First Hospital37,610 enrolled

Overview

Acute kidney injury is one of major adverse postoperative complications. research about postoperative acute kidney injury conclude that low preoperative albumin and intraoperative hypotension is associated to postoperative acute kidney injury. However, due to ethic issue and nonlinear realtionship between these factors and postoperative acute kidney injury, the exact threshold of these two risk factors were not be able to identified. The research tried to locate the exact threshold with implementation of penalized splines by generalized additive model.

Study Type

OBSERVATIONAL

Enrollment

37,610

Conditions

Acute Kidney Injury

Eligibility

Sex: ALLMin age: 18 YearsMax age: 100 Years

Medical Language ↔ Plain English

Inclusion Criteria: adult non-cardiac, non-obsteric, non- kidney elective surgery patients Exclusion Criteria: patients aged \<18 y emergency surgeries without arterial blood pressure cardiac surgeries obstetric surgeries kidney surgeries under local infiltration or MAC first SBP \<100 mmHg

Locations (1)

First hospital Peking University

Beijing, Beijing Municipality, China

Outcomes

Primary Outcomes

incidence and odds ratio of postoperative acute kidney injury

Time frame: 30 days postoperatively in hospital