AMIPE is both a retrospective and prospective study which was designed in order to collect data of patients with acute coronary syndromes and myocardial injury and to improve the knowledge about these conditions.
AMIPE is an observational, multicenter and both retrospective and prospective study enrolling a cohort of consecutive incident patients admitted to participating hospitals with a diagnosis of acute coronary syndrome or myocardial injury from 01/01/2016 to 31/12/2023. The aim of this study is to create a database including a comprehensive characterization of these patients in order to obtain new scientific evidence about these conditions. Informations about the patients will be gathered from in-hospital medical records. A written informed consent is needed for every prospective patients enrolled in the study, In particular, the main objectives of the study are: * document the characteristics of all patients presenting with acute coronary syndrome and myocardial injury; * document the long term outcome rates; * document the therapeutic regimens and investigation conformity of treatment with already established guidelines. Every diagnostic or therapeutic intervention will be in accordance with established guidelines and good clinical practice. Statistics will be conducted utilizing univariate and multivariate analysis for outcomes. In particular for what concerns univariate analysis, ordinal variables will be analysed with t-test and Mann-Whitney Test, whereas categorical responses with Fischer Exact Test and with Pearson Chi-square test. Multivariate analysis will be conducted with logistic regression for dichotomous variables, with mixed generalized linear model for ordinal or nominal variables and with ANOVA or MANOVA for continuous variables.
Study Type
OBSERVATIONAL
Enrollment
11,000
Create a database containing clinical characteristic, clinical presentation, flow indexes and treatment of consecutive incident patients with ACS or myocardial injury.
Policlinico Sant'Orsola-Malpighi, Cardiology Department
Bologna, Bologna, Italy
RECRUITINGOspedale Maggiore Carlo Alberto Pizzardi
Bologna, BO, Italy
RECRUITINGOspedale Morgagni - Pierantoni
Forlì, FC, Italy
RECRUITINGAll cause mortality
Death rate
Time frame: 1 year
All cause mortality
Death rate
Time frame: 3 years
All cause mortality
Death rate
Time frame: 5 years
Major Adverse Cardiac Events (MACEs)
MACEs rate
Time frame: 1 year
Major Adverse Cardiac Events (MACEs)
MACEs rate
Time frame: 3 years
Major Adverse Cardiac Events (MACEs)
MACEs rate
Time frame: 5 years
Cardiovascular risk factors prevalence
Differences in percentage of patients with STEMI or NSTEMI, or type 1 or type 2 myocardial infarction with any risk factors
Time frame: 1 year
Cardiovascular risk factors prevalence
Differences in percentage of patients with STEMI or NSTEMI, or type 1 or type 2 myocardial infarction with any risk factors
Time frame: 3 year
Cardiovascular risk factors prevalence
Differences in percentage of patients with STEMI or NSTEMI, or type 1 or type 2 myocardial infarction with any risk factors
Time frame: 5 year
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Differences in clinical presentation
Prevalence of patients presenting with ST elevation, angina, dyspnea, atypical chest pain, cardiogenic shock, arrhytmias)
Time frame: 3 year
Differences in clinical presentation
Prevalence of patients presenting with ST elevation, angina, dyspnea, atypical chest pain, cardiogenic shock, arrhytmias)
Time frame: 1 year
Differences in clinical presentation
Prevalence of patients presenting with ST elevation, angina, dyspnea, atypical chest pain, cardiogenic shock, arrhytmias)
Time frame: 5 year
Difference diagnosis between myocardial infarction subtypes and between myocardial infarction and myocardial injury
Differences in clinical presentation (ST elevation, angina, dyspnea, atypical chest pain, cardiogenic shock, arrhytmias)
Time frame: 5 year
Differences in flow characteristics
TIMI, TIMI frame count
Time frame: 1 year
Differences in flow characteristics
TIMI, TIMI frame count
Time frame: 3 year
Differences in flow characteristics
TIMI, TIMI frame count
Time frame: 5 year
Differences and impact of periprocedural ischemic complications
Type 4a myocardial infarction, periprocedural myocardial injury
Time frame: 5 year