A Safety and Efficacy Study to Evaluate Rosacea

Inclusion Criteria: * Healthy male and/or female subjects between the ages of 18 and 65 year with rosacea, 10 to 30 papules and pustules (at least 5 lesions within the treatment area on each facial side), and \< 2 nodules * Presence of moderate to severe persistent erythema * Total body weight \>45 kg Exclusion Criteria: * Presence of any skin condition on the face that would interfere with the diagnosis or assessment of rosacea * Extremely dark skin type that would confound the digital analysis of erythema (eg, Fitzpatrick Skin Type 5 or 6) * Excessive facial hair (eg, beards, sideburns, moustaches, etc.), birthmarks, or tattoos that would interfere with diagnosis or assessment of rosacea * Use of tobacco- or nicotine-containing products in excess of the equivalent of 5 cigarettes per day. * Pregnant or nursing females; females of childbearing potential who are unwilling or unable to use an acceptable method of non-hormonal contraception as outlined in this protocol from at least 14 days prior to start of treatment. * Hypersensitivity or allergy to axitinib or any other component of the study treatment * Use within 6 months prior to baseline and during the study of oral retinoids (eg, Accutane®) or therapeutic vitamin A supplements of greater than 10,000 units/day (multivitamins are allowed). * Use within 6 weeks prior to baseline and during the study of vasodilators or α-adrenergic receptor-blocking agents. * Use within 1 month prior to baseline and during the study of 1) topical retinoids to the face, 2) systemic antibiotics know to have an impact on the severity of facial rosacea (eg, containing tetracycline and its derivatives, erythromycin and its derivatives, sulfamethoxazole, or trimethoprim), 3) systemic corticosteroids, or 4) facial light-based therapies