TPE in Rennes Hospital

Rennes University Hospital190 enrolled

Overview

To assess the indications, tolerance and side effects of therapeutic plasma exchange (TPE) performed at a University Hospital over 8 years

Indications were recorded from the patients electronic chart. Side effects were identified from the review of TPE monitoring forms completed prospectively by the nurse who performed the TPE during the course of the procedure

Study Type

OBSERVATIONAL

Enrollment

190

Conditions

Therapeutic Plasma Exchange

Interventions

Therapeutic plasma exchange (TPE)DEVICE

All TPEs were performed by the centrifugation technique using the Fresenius Kabi COMTEC machine

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * All adult patients who underwent TPE in Rennes University Hospital 2011-2018 Exclusion Criteria: * Absence of the monitoring sheet during the EP session * Refusal of patient participation after receipt of the information letter * Persons over the age of majority who are subject to legal protection (protection of justice, guardianship, guardianship)

Locations (1)

Centre Hospitalier Universitaire de Rennes

Rennes, France

Outcomes

Primary Outcomes

Frequency of side effects during Therapeutic plasma exchange

Occurrence of side effects, regardless of their severity during therapeutic plasma exchange sessions (From start of care by the nurse including the preparation for the insertion of peripheral or central venous access to disconnection from the device and removal of peripheral lines or closing the CVC),. Main side effects recorded are hypotension, tachycardia, shock, anaphylaxis, seizure, cardiac arrest, respiratory failure, skin rash, urticaria, catheter dysfunction, catheter related infection hypocalcemia, alkalosis.

Time frame: The inclusion day (retrospective study)

Data from ClinicalTrials.gov

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