Human Epididymis Protein 4 in Women With Severe Preeclampsia / HELLP Syndrome

Ain Shams University110 enrolled

Overview

Pre-eclampsia seems to be associated with a four to five times increase risk of later microalbuminuria and CKD which might suggest a possible direct renal damage from pre-eclampsia

Study Type

OBSERVATIONAL

Enrollment

110

Conditions

Preeclampsia

Interventions

Human epididymis protein 4DIAGNOSTIC_TEST

Human epididymis protein 4 serum level in predicting persistent proteniuria

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 35 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Pregnant women 18-35 years old. 2. Fulfilling the criteria for diagnosis of sever preeclampsia. 3. Fulfilling the criteria for diagnosis of HELLP syndrome Exclusion Criteria: 1. Diabetes mellitus 2. Preexisting renal disease. 3. Chronic hypertension 4. Rheumatologic diseases 5. Adnexal mass.

Outcomes

Primary Outcomes

protein in urine

proteinuria \> 0.3 mg protein / mg creatinine.

Time frame: 12 weeks postpartum

Data from ClinicalTrials.gov

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