Analysis of the effect of dietary intervention based on increased polyunsaturated fatty acid intake on health. Specifically changes in blood lipid profile, as well as proteomic and metabolomic profiles of healthy adults will be analyzed.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Enrollment
30
Assumptions of nutritional intervention: in a randomized manner volunteers will be assigned to one of two groups: a control group which will receive general nutritional recommendations, based on the Polish nutrition pyramid, and the intervention group which will receive nutritional recommendations, based on the Polish nutrition pyramid and will consume at least 4 tablespoons of olive oil or 30 grams of nuts every day for 12 weeks.
Poznan University of Life Sciences
Poznan, Poland
RECRUITINGNutrient intake
Nutrient intake (3-day food records)
Time frame: 12 weeks
Concentrations of lipoproteins and glucose
Serum concentrations of lipoproteins and glucose at baseline and after the intervention \[mg/dl\]
Time frame: 12 weeks
Proteomic analysis of plasma
The aim is to identify biomarkers in the blood and to determine the differences between people from the control and the intervention group
Time frame: 12 weeks
Metabolite concentrations in plasma
Metabolite concentrations in plasma samples are measured by high resolution mass spectrometry at baseline and after the intervention
Time frame: 12 weeks
Body mass
body mass at baseline and after the intervention
Time frame: 12 weeks
Height
height
Time frame: 12 weeks
Percentage body fat
percentage body fat at baseline and after the intervention
Time frame: 12 weeks
Waist circumference
waist circumference at baseline and after the intervention
Time frame: 12 weeks
hip circumference
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hip circumference at baseline and after the intervention
Time frame: 12 weeks