Association of Plasma PTX3 Concentration and Outcomes of STEMI

Indonesian Cardiovascular Research Center335 enrolled

Overview

335 of patients with STEMI treated by primary PCI were assayed for PTX3 measurement by ELISA method. The angiographic and clinical outcomes were evaluated according to the PTX3 concentration.

335 of patients with STEMI treated by primary PCI were assayed for PTX3 measurement by ELISA method using human PTX3 kit. Blood was drawn at the emergency department before primary PCI. The angiographic and clinical outcomes were evaluated and analyzed according to the PTX3 concentration. The angiographic outcome were thrombus grade on initial angiogram and final TIMI flow. The clinical outcome were ECG resolution after primary PCI and all-cause death at 30 days. The plasma PTX3 concentration was then compared based on the outcomes.

Study Type

OBSERVATIONAL

Enrollment

335

Conditions

STEMI Coronary; Ischemic

Interventions

Plasma PTX3 concentrationOTHER

Long pentraxin 3, thrombus burden, final TIMI flow, ST segment resolution, STEMI, primary PCI

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with acute STEMI with symptom onset \<12 h undergoing primary PCI Exclusion Criteria: * Acute STEMI patients who received fibrinolytic therapy

Locations (1)

Indonesian Cardiovascular Research Center

Jakarta, DKI Jakarta, Indonesia

Outcomes

Primary Outcomes

The proportion of thrombus grade 4&5 and final TIMI flow <3

PTX3 concentration was compared based on the outcome

Time frame: Intraprocedure

Data from ClinicalTrials.gov

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