The Alzheimer's disease or related disorders (ADRD) are among the most disabling diseases because of their main features such as cognitive impairment, loss of functional autonomy and behavioural disorders. In absence of current curative treatment, the identification of the predictive risk factors of progression of the disease, evaluated through its main symptoms, represents a major stake of public health. The Investigators aim at developing a regional database, which includes the patient medical records on a prospective basis, in collaboration with the medical and administrative staff and with the University hospital computer science departments. The main objective is to study the predictive factors associated with change in functional autonomy level, measured every 6 to 12 months in centres across Region Auvergne Rhone-Alpes in France. The real-life study population will consist in about 5400 patients with ADRD. The inclusion period will be of 3 years, the length of follow-up of each patient will be of 10 years max for a total study length of 13 years.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Enrollment
5,400
This is study carried out in current practice. Patients are undergoing a medical examination in a memory center, with extensive and systematic evaluations for the study involving the following tests: IADL, DAD6, New AGGIR, NPI, and mini-Zarit) assessing the functions (autonomy, behavior and caregiver burden).
Hôpital Dugoujon
Caluire-et-Cuire, France
RECRUITINGCentre Hospitalier Lyon Sud
Lyon, France
RECRUITINGService de neuro-cognition et neuro-ophtalmologie du Groupement Hospitalier Est
Lyon, France
RECRUITINGCHU Saint-Etienne
Saint-Etienne, France
RECRUITINGCentre Mémoire de Ressources et de Recherche de Lyon
Villeurbanne, France
RECRUITINGFunctional autonomy level
The Lawton Instrumental Activities of Daily Living (IADL)
Time frame: from 6 months to 12 months interval
Functional autonomy level
The Disability Assessment of Dementia (DAD-6)
Time frame: from 6 months to 12 months interval
Functional autonomy level
The New-AGGIR (French national score for dependency assessment)
Time frame: from 6 months to 12 months interval
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