Ovarian Reserve in Crohn's Disease

Kanuni Sultan Suleyman Training and Research Hospital100 enrolled

Overview

Crohn's disease reduces fertility by inducing inflammation both directly and in the fallopian tubes and ovaries and indirectly through surgical interventions and tubal adhesions associated with disease treatment. Anti-mullerian hormone (AMH) is a reliable indicator of ovarian reserve in women. The aim of this study was to compare serum AMH levels in women with Crohn's disease and healthy controls. In this study, the investigators aimed to investigate AMH and ovarian capacity in the study group with crohn's disease and in the control group without disease.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Crohn Disease Ovary Disease Anti-Mullerian Hormone Deficiency

Interventions

AMH levels in young women with crohn's disease will be considered.

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * crohn's disease; * reproductive age women Exclusion Criteria: * Over 40 years old, * a previous ovarian resection; * renal failure (serum creatinine levels N1.2 mg / dL);suspicion of malignancy; * the presence of hereditary or acquired hematological disease; * pregnancy; * current lactation; * the presence of a serious comorbid chronic disease; * cirrhosis originating from chronic liver disease; * abnormal thyroid function tests; * a known serious psychological problem; * presence of alcoholism and male sex.

Outcomes

Primary Outcomes

AMH levels

AMH levels of subjects taken into groups will be evaluated in lg/L

Time frame: 1 MONTH

Secondary Outcomes

ultrasound findings

On the 3rd day of the menstrual cycle, the patients will be given ultrasound and the ovarian volume will be examined. the ovarian volume will be calculated by taking the size of the ovary in three sections.