Transcranial direct current stimulation (tDCS) is a technique of noninvasive cortical stimulation allowing significant modification of brain function used. Clinical application of this technique could be helpful for pain, Parkinson's disease, dystonia, cerebral palsy and dementia etc. And tDCS is safe with only mild, transient adverse effects. But there is few studies focused to postoperative states. The aim of this project is to reveal the effect of tDCS for postoperative pain after total knee replacement surgery,
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Enrollment
70
Intensity 2mA, 20minues, 4 times (post operation in 30min, in 4hrs, next day morning and next day afternoon) anodal tDCS applied over the left DLPFC cathodal tDCS applied over the right DLPFC
Intensity 0mA, 40 seconds, 4 times (post operation in 30min, in 4hrs, next day morning and next day afternoon) anodal tDCS applied over the left DLPFC cathodal tDCS applied over the right DLPFC
Seoul Metropolitan Government Seoul National University Boramae Medical Center
Seoul, South Korea
VAS score
the decrease of pain scale in postop state with Visual Analog Scale.
Time frame: 1hour, 6hours, 24 hours, 48 hours
Incidence of Delirium
Incidence of Delirium
Time frame: postop day 1,3,6
Consumption of PCA
The consumption of opioid.
Time frame: 24 hours
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