Multi-modal Imaging and Artificial Intelligence Diagnostic System for Multi-level Clinical Application

Inclusion Criteria: Group A(normal individuals): Meet all the items 1 \~ 5 below 1. No familial or hereditary retinopathy; 2. No history of ocular trauma and / or history of ocular disease (except for mild to moderate refractive errors and / or age-related cataracts); 3. No drug use history that may cause side effects of retina (such as chloroquine, hydroxychloroquine, chlorpromazine, rifampin, etc.); 4 binocular diopter ≤ ± 6.00D; No systemic diseases that may affect the retina. Group B(diabetes patients without ocular complications): meet any of 1 to 3, and both 4 to 5 items 1. Diagnosed with type 1 diabetes for more than 5 years; 2. Diagnosed with type 2 diabetes patients; 3. Diagnosis of gestational diabetes patients; 4. Without systemic disease that may affect the retina except for diabetes; 5. Meet the standards of 1 to 4 items. Group C(patients with diabetic ocular complications): meet with any of 1 to 3, and all 4 to 6 items 1. Diagnosed with type 1 diabetes for more than 5 years; 2. Diagnosed with type 2 diabetes patients; 3. Diagnosis of gestational diabetes patients; 4. Meet the guidelines for diagnosis and treatment of diabetic retinopathy in any stage of diabetic retinopathy and / or diabetic macular edema. 5. Without systemic disease that may affect the retina except for diabetes; 6. A group to meet the criteria for 1 to 4 items. Exclusion Criteria: 1. Refractive pathway is turbid, so that fundus image can not be clearly photographed; 2. With other fundus diseases and / or other diseases that seriously affect the visual function; 3. Any eye infection, such as conjunctivitis, keratitis, scleritis, endophthalmitis, acute and chronic dacryocystitis, or eye injury; 4. Serious systemic diseases such as diabetes, hypertension, heart failur,renal failure; 5. Can not cooperate with the examiner due to mental or other reasons.