This trial studies comprehensive geriatric and quality of life assessments in older patients with head and neck or lung cancer that has or has not spread to other parts of the body who are undergoing standard surgery or chemoradiation, and their caregivers. Comprehensive geriatric assessment may improve the quality of life of patients with head and neck or lung cancer and their caregivers.
PRIMARY OBJECTIVES: I. To describe the patterns and distribution of comprehensive geriatric assessment (CGA) scores and physical activity levels and quality of life measures in older (\>= 65) patients with non-metastatic or metastatic head and neck or lung cancer undergoing upfront surgery followed (may be followed by adjuvant therapy) or upfront definitive radiation (with or without chemotherapy at the same time) to cure the disease. II. To describe the incidence and type of grade 2-5 toxicities in this patient population. III. To describe the family caregiver (FCG)-reported caregiving burden level and quality of life (QOL) scores. SECONDARY OBJECTIVES: I. To identify areas of vulnerability in this patient population using the geriatric assessment. II. To identify potential referrals based on geriatric assessment results. III. To describe other healthcare resource use and potential treatment modifications (unplanned hospitalization, emergency room (ER) visits, readmission rates, breaks in radiation and/or chemoradiation (CRT), dose modifications). IV. To explore changes in geriatric assessment and patient-reported symptoms, QOL, weight, and functional status from pre-treatment to 3-months, 6 months post-treatment. V. To explore changes in family caregiver (FCG)-reported caregiving burden and QOL from pre-treatment to 3-months, 6 months post-treatment. VI. To explore the relationship between geriatric assessment results and patient-reported symptoms and QOL. OUTLINE: Participants are assigned to 1 of 2 groups. GROUP I: Patients complete comprehensive geriatric and quality of life assessments within 1-4 weeks of treatment (either upfront surgery which may be followed by radiation with or without chemotherapy or upfront radiation which may include CRT) initiation (baseline), and at 1, 3, and 6 months following CRT completion. GROUP II: Family caregivers complete quality of life assessment at baseline, and at 1, 3, and 6 months following patient radiation or CRT completion.
Study Type
OBSERVATIONAL
Enrollment
28
Complete comprehensive geriatric assessment
Complete quality of life assessment
Complete questionnaires
City of Hope Medical Center
Duarte, California, United States
Comprehensive geriatric assessment (CGA) scores and domains
Descriptive statistics will be used to summarize all CGA measure scores/domains.
Time frame: Up to 6 months post therapy
Physical activity levels
Descriptive statistics will be used to summarize all physical activity levels.
Time frame: Up to 6 months post therapy
Quality of life (QOL) measures
Descriptive statistics will be used to summarize all QOL measures.
Time frame: Up to 6 months post therapy
Incidence and type of grade 2-5 toxicities
Types of grade 2-5 toxicities will be summarized and proportions of patients with grade 2-5 toxicities will be tabulated and reported according to Common Terminology Criteria for Adverse Events (CTCAE) 4.0.
Time frame: Up to week 4
Family caregiver (FCG)-reported caregiving burden level and QOL scores
Descriptive statistics will be used to summarize all FCG-reported measure scores/domains.
Time frame: Up to 6 months post therapy
Percentage of patients with vulnerability using the geriatric assessment
Percentage of patients with vulnerability will be calculated as the number of patients with vulnerability divided by 30 (target sample).
Time frame: Up to 6 months post therapy
Percentage of patients who receive and accept referrals
The percentage of patients who receive and accept referrals will be calculated as the number of patients with referral divided by the number of patients with vulnerability.
Time frame: Up to 6 months post therapy
Treatment modification and healthcare utilization in patients
Frequency and reasons for healthcare resource use and treatment modifications will be tabulated.
Time frame: Up to week 12
Change in CGA scores and domains
Changes will be calculated as post-treatment scores minus pre-treatment scores. The pattern of changes in CGA assessment will be summarized.
Time frame: Baseline up to 6 months post therapy
Change in physical activity levels
Will utilize the pedometer to assess physical activity level during and after treatment and record changes. The pattern of changes in physical activity levels will be summarized.
Time frame: Baseline up to 6 months post therapy
Change in QOL measures
Changes will be calculated as post-treatment scores minus pre-treatment scores. The pattern of changes in QOL measures will be summarized.
Time frame: Baseline up to 6 months post therapy
Change in FCG-reported caregiving burden level and QOL scores
Changes will be calculated as post-treatment scores minus pre-treatment scores.
Time frame: Baseline up to 6 months post therapy
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