This study aimed to evaluate the efficacy of low-dose rosuvastatin (10 mg) in the 4 statin benefit groups requiring high- or moderate-intensity statin therapy according to the 2013 American College of Cardiology/American Heart Association guideline in Korean population.
The primary endpoint was percentage reduction in low-density lipoprotein (LDL) cholesterol. Secondary endpoints were percentage reduction in other lipids and achievement of ≥50% reduction in LDL cholesterol. Intention-to-treat analyses were performed.
Study Type
OBSERVATIONAL
Enrollment
242
Low-dose (10mg) rosuvastatin in 4 statin benefit groups per 2013 ACC/AHA guideline
Percentage reduction in low-density lipoprotein (LDL) cholesterol
Percentage reduction in low-density lipoprotein (LDL) cholesterol from baseline to 8 weeks of treatment
Time frame: 8 weeks
Percentage reduction in other lipids
Percent changes from baseline to 8 weeks in total cholesterol, high-density lipoprotein (HDL) cholesterol, triglyceride (TG), non-HDL cholesterol, apolipoprotein B, apolipoprotein A1
Time frame: 8 weeks
Achievement of ≥50% reduction in LDL cholesterol
Achievement of ≥50% reduction in LDL cholesterol with use of rosuvastatin 10 mg in 8 weeks
Time frame: 8 weeks
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