This retrospective analysis is to investigate patients' history and clinical presentation in Herpes Zoster (HZ), Zoster-related complications, post-Zoster neuralgia and Herpes Zoster management in order to improve the management of HZ patients, to refine HZ-vaccination strategies and elucidate cost factors of HZ in in the setting of a university hospital in Switzerland generally and in a dermatology department specifically.
Study Type
OBSERVATIONAL
Enrollment
355
retrospective report review of HZ patients treated between 2005 and 2018 in the Department of Dermatology at the University Hospital Basel
Department of Dermatology, University Hospital Basel
Basel, Switzerland
Evaluation of patients' history
Free text evaluation of patients' history (age, sex, comorbidities, immunosuppression, obesity, human immune deficiency Virus (HIV), profession, current medication, vaccinations, seasonal occurence of HZ, history of Varicella Zoster virus (VZV) infection
Time frame: single time point assessment at baseline
Description of the clinical presentation of HZ
Free text description of the clinical presentation of HZ (localisation, dermatomes affected), Zoster-related acute pain
Time frame: single time point assessment at baseline
Evaluation of zoster-related complications
Free text evaluation of zoster-related complications (ophthalmic zoster, generalised HZ, Ramsay-Hunt syndrome, zoster meningoencephalitis)
Time frame: single time point assessment at baseline
Evaluation of the herpes zoster management
Free text evaluation of the herpes zoster management (local (antiviral) treatment, systemic antiviral and other treatments, number of revisits, average treatment-related costs, hospitalisations (rate, duration)
Time frame: single time point assessment at baseline
Assessment of post-zoster neuralgia
Free text assessment of post-zoster neuralgia (annual incidence, treatment options used)
Time frame: single time point assessment at baseline
Evaluation of zoster and pregnancy
Free text evaluation of zoster and pregnancy (incidence, time of pregnancy, pregnancy outcomes and complications)
Time frame: single time point assessment at baseline
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