Mindfulness-based Cognitive Therapy (MBCT) for People With Parkinson's Disease

University of California, San Francisco16 enrolled

Overview

This study aims to explore the feasibility and effectiveness of mindfulness-based cognitive therapy (MBCT) in reducing anxiety and/or depressive symptoms in people with Parkinson's disease.

An adapted MBCT intervention will be offered to people with Parkinson's disease and mild-to-moderate depression and/or anxiety. Two 8-week long MBCT groups will be held between September 2019 and March 2020, based on the adapted protocol. Modifications will include shortening the traditional 120-minute to 90-minute format and performing mindful yoga from a chair, instead of a floor mat. Participants will be recruited from the community, according to the eligibility criteria detailed below. The participants' pre- and post-MBCT anxiety and/or depressive symptom severity and mindfulness levels (as measured with standardized, validated scales) will be compared, using a paired t-test.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Parkinson Disease Anxiety Depression

Interventions

Mindfulness-based cognitive therapy (MBCT)BEHAVIORAL

MBCT is an evidence-based psychotherapy which combines mindfulness skills with cognitive therapy strategies.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Diagnosis of Parkinson's disease or parkinsonism (established by a neurologist) 2. Living in the San Francisco Bay Area 3. Being able and willing to attend 8 weekly 90-minute group sessions 4. Mild-to-moderate anxiety: GAD-7 score ≤ 16 5. Mild-to-moderate depression: PHQ-9 score ≤ 18 Exclusion Criteria: 1. Severe anxiety: GAD-7 score \> 16 2. Moderately severe-to-severe depression: PHQ-9 score \> 18 3. Cognitive impairment: Montreal Cognitive Assessment (MoCA) score \< 24 4. Heavy alcohol or drug use 5. Severe psychosis 6. Active suicidal or homicidal ideation 7. Severe motor fluctuations (less than 2 hours "on" time per day)

Locations (1)

University of California, San Francisco

San Francisco, California, United States

Outcomes

Primary Outcomes

Change in anxiety symptom severity

Change in Generalized Anxiety Disorder-7 item score (for participants with anxiety). The scale score range is 0-21, with higher scores indicating more severe anxiety.

Time frame: From pre- to post-MBCT 8 weeks later

Change in depressive symptom severity

Change in Patient Health Questionnaire-9 score (for participants with depression). The scale score range is 0-27, with higher scores indicating more severe depression.

Time frame: From pre- to post-MBCT 8 weeks later

Secondary Outcomes

Change in mindfulness levels

Change in 15 item-Five Facet Mindfulness Questionnaire score. The scale score range is 0-75, with higher scores indicating higher mindfulness levels.

Time frame: From pre- to post-MBCT 8 weeks later

Time spent practicing mindfulness

Number of minutes per week spent practicing mindfulness exercises

Time frame: During MBCT group (8 week-period)

Data from ClinicalTrials.gov

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