Objective of the study: to evaluate whether alfieri technique improves clinical and hemodynamic results compared to transaortic mitral valve secondary cord cutting in patients scheduled to septal myectomy for severely symptomatic hypertrophic obstructive cardiomyopathy.
There is pilot prospective randomised study comparing immediate and early results of additional subvalvular mitral apparatus intervention versus additional alfieri stich in patients scheduled to septal myectomy for symptomatic obstructive cardiomyopathy. Patients with proven hypertrophic cardiomyopathy and resting left ventricle outflow tract obstruction underwent septal myectomy. If patients were suitable for both surgical techniques, they were randomized to alfieri stich or secondary cord cutting. All surgeons were experienced at least 50 related procedures.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
48
Transaortic septal myectomy
Transaortic Mitral valve repair using alfieri technique
Transaortic Mitral valve subvalvular intervention including anterior mitral leaflet secondary cord cutting, papillary muscle release
Novosibirsk State Research Institute of Circulation Pathology
Novosibirsk, Russia
Transmitral pressure gradient
Transmitral pressure gradient after the procedures assessed by echocardiography
Time frame: 30-days
Repeat bypass
Rate of second cross clamping and repeating bypass for procedure related reasons
Time frame: 30 day
Residual left ventricle outflow tract gradient
Residual left ventricle outflow tract gradient assessed by direct measurement
Time frame: intraoperative measuerment
Early mortality
All cause death during 30 days
Time frame: 30 days
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.