Comparison of Two Diagnostic Tests in Patients With Suspected Invasive Candidiasis in Internal Medicine Wards and Who Are Currently Timely Treated With Micafungin

Inclusion Criteria: * Age 18 years * Patients giving their informed consent to participate to the study and to the use of their health data * Patients with two or more SIRS criteria (hyperthermia, or hypothermia, tachycardia, tachypnea, leucocytosis or leukopenia ) * Patients treated with antibiotic therapy in the last 4 weeks and with central venous catheter * Patients with at least one of these conditions ( cortisone therapy/ immunosuppressive agents, total parenteral nutrition, urinary catheter, anticancer chemotherapy and major surgery in the last 3 weeks, acute pancreatitis, diabetes mellitus, liver diseases, dialysis) Exclusion Criteria: * Patients with ALT, AST, bilirubin \> 3 times the upper limit of normal * Patients enrolled in other interventional clinical studies * Patients treated with echinocandin or azolic or polyene at the time of the enrolment * Pregnancy or breastfeeding * Neutropenic patients * HIV positive patients * Central nervous system events