Bloodstream Infections in Patients With Rheumatoid Arthritis

Sabine Dieperink6,000,000 enrolled

Overview

Study of incidence and risk factors of staphylococcus aureus bacteremia in patients with rheumatoid arthritis compared with the general population in a nationwide cohort of all adult members of the population from 1996 until 2017 using national registries

Study Type

OBSERVATIONAL

Enrollment

6,000,000

Conditions

Rheumatoid Arthritis Staphylococcus Aureus Bacteremia

Interventions

Risk factors in RA cohortOTHER

Risk factors in general populationOTHER

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * All members of the adult Danish population Exclusion Criteria: * Staphylococcus aureus bacteremia prior to inclusion. * Rheumatoid arthritis diagnosed prior to inclusion.

Outcomes

Primary Outcomes

Incidence of staphylococcus aureus bacteremia

Time frame: 0-21 years

Incidence rate ratios

Comparing rheumatoid arthritis patients with the general population

Time frame: 0-21 years

Secondary Outcomes

Risk factors of staphylococcus aureus bacteremia

Identification of risk factors both universal to both the general population and rheumatoid arthritis (RA) cohorts and RA disease specific factors (disease duration, disease activity, smoking, joint erosions, etc.)

Time frame: 0-21 years

Data from ClinicalTrials.gov

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