Optimized Treatment Strategies for Early and Medium Stage Nasopharyngeal Carcinoma

Inclusion Criteria: * Pathology confirmed nasopharyngeal squamous cell carcinoma. * Aged 18 to 70 years old; * Stage II-III (T1N1M0，T2-3N0-1M0) diseases according to 8th AJCC Staging and the shortest diameter of the largest lymph node involved is no more than 3cm; * KPS≥70; * Have measurable lesions on CT/MRI before treatment; * Treatment for the first time; * At least 6 months lifetime was expected; * Adequate laboratory indexes, defined as follows: Hemoglobin \> 120g/L, WBC \> 4.0x10\*9/L, Plt \> 100x10\*9/L \< 2, all indexes of liver and kidney function ≤ 1.25 times of the institutional upper limit of normal value, no hearing loss; * Can understand and sign the consent * Have follow up condition Exclusion Criteria: * Past malignancies history (except for stage I non-melanoma skin cancer or cervical carcinoma in situ) * Previously treatment for cancer * Pregnant or breeding woman, female without contraception * Enrolling in other drug trials * Severe comorbidities including myocardial infarction, arrhythmia, cerebral vascular disease, ulceration disease, mental disease and uncontrolled diabetes * Without follow up