We investigated the effects of whole body vibration (WBV) and high-impact (HI) exercises in postmenopausal women with low bone mineral density. In summary, WBV exercises are effective in preventing bone loss and WBV and HI exercise programs are effective in decreasing fall risk, increasing health-related quality of life and improving depressive symptoms
Purpose: The aim of this study was to determine the effects of six months of supervised whole-body vibration (WBV) and high-impact (HI) exercises on bone mineral density (BMD), serum bone turnover markers, fall risk, health-related quality of life (HRQoL) and depressive symptoms in postmenopausal women, additionally, to evaluate the advantage of each training program to another. Methods: In a prospective, randomized controlled 6-month interventional trial 58 eligible postmenopausal women were assigned to WBV training group (n=19), HI training group (n=19), or control group (n=20). The patients in both training groups participated in a supervised training program, which consisted of the one-hour exercise session three times a week for six months. The WBV groups received vibration (30-35 Hz, 2-4 mm) in five different static positions. The HI group jumped rope (10-50 jumps/day). All patients received calcium (1000 mg) and vitamin D (880 IU) supplementation per day. In all participants, baseline and six-month BMD at the lumbar spine and femur were measured by Dual-energy X-ray Absorptiometry (DXA). Serum osteocalcin (OC) and C-terminal telopeptide of type I collagen (CTx) were measured at baseline, three- and six-month intervals. Fall risk was assessed by using the Timed Up and Go (TUG) test and fall index measured by static posturography at baseline, three- and six-month intervals. HRQoL and depressive symptoms were assessed using the Quality of Life Questionnaire of the European Foundation for Osteoporosis (QUALEFFO) and Beck Depression Inventory (BDI), respectively, at baseline and six-month of the study.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
58
The WBV training consisted of a high frequency (30-40 Hz) vibration stimulus at a low setting on a Power Plate pro5 vibration platform (Performance Health Systems, LLC, Northbrook, IL, USA).
In the high-impact exercise program, the patients were asked to jump using a jump-rope at the beginning of each session
Change from Baseline Bone Mineral Density at 6 months
The bone mineral density of the lumbar spine, femoral neck were measured with a dual energy x-ray absorptiometry
Time frame: baseline and 6 month
Change from Baseline Bone Formation Marker at 3-months and 6-months
The serum osteocalcin (OC) level
Time frame: baseline, 3-month, 6-month
Change from Baseline Bone Resorption Marker- at 3-months and 6-months
The serum C-terminal telopeptide of type I collagen (CTx) levels
Time frame: baseline, 3-month, 6-month
Change from Baseline Fall risk at 3-months and 6-months
A computerized static posturography device was used to measure the fall index
Time frame: baseline, 3-month, 6-month
Change from Baseline Functional Balance at 3-months and 6-months
Timed Up and Go (TUG) test
Time frame: baseline, 3-month, 6-month
Change from Baseline Health-related Quality of Life at 6 months
Quality of Life Questionnaire of the European Foundation for Osteoporosis (QUALEFFO)
Time frame: baseline, 6-month
Change from Baseline Depressive Symptoms at 6 months
Beck Depression Inventory
Time frame: baseline, 3-month, 6-month
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