TEAS Reduces Remifentanil Consumption

Air Force Military Medical University, China153 enrolled

Overview

Transcutaneous electrical acupoint stimulation (TEAS) has been shown to decrease the need of opioids including remifentanil during anaesthesia. However, it is not clear whether combination of two or more acupoints could induce stronger analgesia. Moreover, evidence for the long-term effect of TEAS has been limited. The present study was to compare the short-term and long-term effect on pain of dual-acupoint and single-acupoint TEAS.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

153

Conditions

Anesthesia Pain

Interventions

acupoint stimulationDEVICE

single acupointDEVICE

dual acupointsDEVICE

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * 18 to 65 yrs * body mass index (BMI) of 18 to 30 kg/m2 * elective radical mastectomy under general anaesthesia Exclusion Criteria: * contradictions to TEAS * difficulties in communication * histories of general anaesthesia * drug or alcohol abuse or addiction * cardiac dysfunction or severe hypertension * confirmed hepatic dysfunction and renal impairment * the participants recruited into other clinical trials during last three months

Outcomes

Primary Outcomes

consumption of remifentanil

Time frame: from start of anesthesia to extubation, on average 2 hours

Secondary Outcomes

time to recall

Time frame: from end of remifentanil infusion to patient response to verbal command,approximately 10 minutes on average

time to extubation

Time frame: from end of remifentanil infusion to extubation,approximately 10 minutes on average

respiratory depression

Time frame: end of the surgery to discharge from postanesthesia care unit,with an average of 30 minutes

nausea and vomiting

Time frame: end of the surgery to discharge from postanesthesia care unit,with an average of 30 minutes

visual analogue scale of pain

pain intensity is assessed by a 0-10mm scale, 0 is no pain, 10 is untolerated pain

Time frame: end of the surgery to discharge from postanesthesia care unit,with an average of 30 minutes

patients' satisfaction score

patients' satisfaction score is assessed by a 0-10mm scale, 0 is no pain, 10 is untolerated pain

Time frame: from end of surgery to 24 hours after surgery, totally 24 hours

incidence of pain at 3m after surgery

percentage of patients suffering from pain around the incision

Time frame: from discharge from hospital to 3 months after surgery, approximately 3 months

incidence of pain at 6m after surgery

Data from ClinicalTrials.gov

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