The Safety and Efficacy of SYD-101 in Children With Myopia

Inclusion Criteria: * Myopia of 0.5 D (diopters) to 6.00 D (inclusive) in both eyes. * Astigmatism ≤1.50 D in both eyes. * Anisometropia ≤1.00 D in both eyes. * If myopia is ≥0.75 D, participant must be wearing single vision eyeglasses or soft, daily-wear, single-vision contact lenses that meet study investigator's criteria. * BCVA (best-corrected visual acuity) Snellen equivalent of 20/32 or better. Exclusion Criteria: * Participants with a history or current evidence of a medical condition predisposing them to degenerative myopia (e.g. Marfan syndrome, Stickler syndrome), or a condition that may affect visual function or development (e.g. diabetes mellitus, chromosome anomaly). * Current use of a monoamine oxidase inhibitor. * Evidence of any ocular inflammation or infection in either eye, including blepharitis, conjunctivitis, keratitis, and scleritis. * Past, present or future plans to use orthokeratology (orthoK), rigid gas-permeable, bifocal, progressive-addition, multi-focal, or other lenses to reduce myopia progression; or the use of atropine, pirenzepine or other anti-muscarinic agent for myopia. * History or evidence of ocular surgery or planned future ocular surgery in either eye. Other protocol-defined inclusion/exclusion criteria could apply.