Aim of this study is to conduct longitudinal and cross-sectional analyses about the corneal ectatic disease Keratoconus based on data obtained from Keratoconus patients in the Homburg Keratoconus Center (HKC). The Homburg Keratoconus Center (HKC) was founded in 2010 and, up to now, comprises more than 3,000 Keratoconus patients. Topographic, tomographic and biomechanic characteristics of the disease are being analyzed with the intention to elucidate how the disease begins and develops during lifetime.
Study Type
OBSERVATIONAL
Enrollment
5,000
The study is based upon data obtained during routine medical follow-ups using 1. the Pentacam high resolution (Oculus, Wetzlar, Germany) 2. the Corvis ST (Oculus, Wetzlar, Germany) 3. the Anterior-Segment Optical Coherence Tomograph (AS-OCT) Casia 2 (Tomey, Nagoya, Japan) 4. the Ocular Response Analyzer (Reichert Technologies, New York, USA).
Department of Ophthalmology
Homburg, Saarland, Germany
RECRUITINGAn overview about development of anterior corneal curvature in Keratoconus disease during lifetime.
The anterior radius of curvature (ARC, 3mm zone) of Keratoconus patients as measured by the Pentacam high resolution (Oculus, Wetzlar, Germany) at different ages (according to: Belin MW and Duncan JK. Keratoconus: The ABCD grading system. Klin Monbl Augenheilkd. 2016; 233(6): 701-707) is put into relation to the age of the Keratoconus patients.
Time frame: 01/01/2011-01/01/2019
An overview about development of posterior corneal curvature in Keratoconus disease during lifetime.
The posterior radius of curvature (PRC, 3mm zone) of Keratoconus patients as measured by the Pentacam high resolution (Oculus, Wetzlar, Germany) at different ages (according to: Belin MW and Duncan JK. Keratoconus: The ABCD grading system. Klin Monbl Augenheilkd. 2016; 233(6): 701-707) is put into relation to the age of the Keratoconus patients.
Time frame: 01/01/2011-01/01/2019
An overview about development of the thinnest corneal pachymetry in Keratoconus disease during lifetime.
The thinnest corneal pachymetry of Keratoconus patients as measured by the Pentacam high resolution (Oculus, Wetzlar, Germany) at different ages (according to: Belin MW and Duncan JK. Keratoconus: The ABCD grading system. Klin Monbl Augenheilkd. 2016; 233(6): 701-707) is put into relation to the age of the Keratoconus patients.
Time frame: 01/01/2011-01/01/2019
An overview about development of the best corrected distance visual acuity in Keratoconus disease during lifetime.
The best corrected distance visual acuity of Keratoconus patients as raised as part of the clinical examination at different ages (according to: Belin MW and Duncan JK. Keratoconus: The ABCD grading system. Klin Monbl Augenheilkd. 2016; 233(6): 701-707) is put into relation to the age of the Keratoconus patients.
Time frame: 01/01/2011-01/01/2019
Reproducibility study: Kmax.
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Measurements of Kmax measured by different devices (Pentacam high resolution, Oculus, Wetzlar, Germany; Anterior-Segment Optical Coherence Tomograph (AS-OCT) Casia 2, Tomey, Nagoya, Japan) are being compared and set into relation at different Keratoconus stages with the intention to investigate, whether measurement inaccuracies occur at later Keratoconus stages using different devices.
Time frame: 01/01/2011-01/01/2019
Reproducibility study: Thinnest corneal pachymetry.
Measurements of the thinnest corneal pachymetry as measured by different devices (Pentacam high resolution, Oculus, Wetzlar, Germany; Anterior-Segment Optical Coherence Tomograph (AS-OCT) Casia 2, Tomey, Nagoya, Japan) are being compared and set into relation at different Keratoconus stages with the intention to investigate, whether measurement inaccuracies occur at later Keratoconus stages using different devices.
Time frame: 01/01/2011-01/01/2019
Reproducibility study: Thinnest corneal pachymetry at the apex position.
Measurements of the thinnest corneal pachymetry at the apex position as measured by different devices (Pentacam high resolution, Oculus, Wetzlar, Germany; Anterior-Segment Optical Coherence Tomograph (AS-OCT) Casia 2, Tomey, Nagoya, Japan) are being compared and set into relation at different Keratoconus stages with the intention to investigate, whether measurement inaccuracies occur at later Keratoconus stages using different devices.
Time frame: 01/01/2011-01/01/2019