the Efficacy and Safety of Blueberry Yeast Fermentation Freeze Dying Powder on Promotion of Immunity

Inclusion Criteria: * Adult men and women over 50 years * After fully hearing and fully understanding this clinical trials, those who agree to voluntarily decide to participate and to comply with the notice Exclusion Criteria: * If screening shows that the white blood cell(WBC) is less than 3000/㎕ or more than 8000/㎕ * Those who received influenza vaccination within 3 months before the screening * Those who have a body mass index(BMI) of less than 18.5 kg / m2 or greater than 35 kg / m2 at the screening * Those who have a clinically significant acute or chronic cardiovascular system, endocrine system, immune system, respiratory system, liver biliary system, kidney and urinary system, neuropsychiatry, musculoskeletal system, inflammatory and hematologic * Those who take a medication or health function food that affects your promotion of immunity within 1 month prior to the screening * Those who have received antipsychotic medication within 3 months before screening * Those who alcoholic or drug abuse suspected * Those who participated in other clinical trials within 3 months before screening * Laboratory test by show the following results * Aspartate Transaminase(AST), Alanine Transaminase(ALT) \> Reference range 3 times upper limit * Serum Creatinine \> 2.0 mg/dL * Pregnancy or breast feeding * Those who doesn't accept the implementation of appropriate contraception of a childbearing woman * Principal Investigator judged inappropriate for participation in study because of Laboratory test result, etc.