Predictive Factors of Inadequate Bowel Preparation in Inpatients

IRCCS Azienda Ospedaliero-Universitaria di Bologna1,658 enrolled

Overview

About 50-70% only of inpatients who undergo colonoscopy have an adequate bowel cleansing, which is far below the recommended threshold of 90%. Variables associated to inadequate colon preparation have not been assessed yet. Identifying such variables would allow to augment the diagnostic yield of colonoscopy, and also to reduce costs related to the need to repeat colonoscopy. Aim of the present study is to find variables independently associated to an inadequate bowel cleansing and to subsequently build and validate a predictive model, which could prove useful in clinical practice to identify hard-to-prepare inpatients. Secondary endpoints are (i) to assess the proportion of patients with inadequate colon cleansing, (ii) to run a cost-effectiveness analysis between patients with adequate cleansing and patients who need to repeat colonoscopy. Patients undergoing urgent colonoscopy, and patients who take the preparation at home will be excluded.

Study Type

OBSERVATIONAL

Enrollment

1,658

Conditions

Bowel Preparation Solutions Colonoscopy Inpatient

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Inpatient ≥18 y.o. who are scheduled elective colonoscopy during hospitalization irrespective of the indication. Exclusion Criteria: * Urgent colonoscopy * Patients who are not hospitalized when taking bowel preparation or when undergoing colonoscopy

Outcomes

Primary Outcomes

Inadequate bowel cleansing rate

The number of inpatients with inadequate bowel preparation over the total number of patients enrolled. Bowel prep will be assessed according to the Boston Bowel Preparation Scale (BBPS). A score less than 2 at one segment of the colon will be considered as inadequate bowel preparation.

Time frame: At the end of the study, 3 months after the beginning of the study.

Secondary Outcomes

Rate of patients scheduled for colonoscopy repetition due to inadequate bowel preparation

Total number of patients scheduled for repeating colonoscopy over the total number of patients enrolled scheduled for repeating colonoscopy due to poor bowel pre.