Several neuropeptides have concerned with epilepsy pathogenesis, ghrelin showed an anticonvulsant effect. There is a potential relation between its level and antiepileptic drugs (AED) response.
Several neuropeptides have concerned with epilepsy pathogenesis, ghrelin showed an anticonvulsant effect. There is a potential relation between its level and antiepileptic drugs (AED) response. Objective: to evaluate ghrelin effect in adult epileptic patients and in response to AED. Methods: This case control study included 40 adult epileptic patients and 40 healthy controls. Participants were subjected to history taking of seizure semiology, full general and neurological examination, electroencephalography and cranial CT or MRI. Fasting serum acylated ghrelin (AG) and unacylated ghrelin (UAG) and urine AG levels were estimated to all participants by enzyme - linked immunosorbent assay (ELIZA).
Study Type
OBSERVATIONAL
Enrollment
80
Nageeb
Zagazig, Sharqia Province, Egypt
Serum ghrelin in Adult Epileptic Patients
evaluation of the effect of Serum ghrelin in adult epileptic patients and in their response to anti- epileptic drugs
Time frame: 6 months
Urine ghrelin in Adult Epileptic Patients
evaluation of the effect of Urine ghrelin in adult epileptic patients and in their response to anti- epileptic drugs
Time frame: 6 months
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