Surgical Outcome of Macular Membrane Peeling Associated With Significant Macular Drusen

Klinikum Chemnitz gGmbH40 enrolled

Overview

Surgical outcome of patients with macular drusen and co-existing abnormalities of the vitreoretinal interface, who routinely undergo pars plana vitrectomy with membrane peeling, is evaluated. Best corrected visual acuity as well as optical coherence tomography data are compared at baseline and last follow up. The rate of development of choroidal neovascularization postoperatively is noted.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Epiretinal Membrane Macular Holes Age Related Macular Degeneration

Interventions

pars plana vitrectomy with membrane peelingPROCEDURE

23-gauge pars plana vitrectomy with peeling of the epiretinal and internal limiting membrane as well as air- or gastamponade

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. participants diagnosed with ERM or FTMH and co-existing macular drusen; 2. undergone pars plana vitrectomy with ILM and epiretinale membrane peeling; 3. SD-OCT at the initial visit and at last follow up visit with image quality score \>30; 4. no evidence of CNV on initial fluorescein angiography (FA). Exclusion Criteria: 1. history of other macular disease, severe non-proliferative or proliferative diabetic retinopathy, other retinal vascular diseases, glaucoma, myopic retinopathy, or other diseases interfering with OCT images in any one of the eyes; 2. active CNV or history of CNV

Locations (1)

Klinikum Chemnitz, Ophthalmology Department

Chemnitz, Saxony, Germany

Outcomes

Primary Outcomes

number of patients with CNV

number of patients with CNV (choroidal neovascularization) development

Time frame: last visit, in common 6 months postoperatively

Secondary Outcomes

BCVA

best corrected visual acuity

Time frame: last visit, in common 6 months postoperatively

incidence of central retinal atrophy

development of central retinal atrophy on OCT

Time frame: last visit, in common 6 months postoperatively

Data from ClinicalTrials.gov

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