Incidence of ST-segment Elevation Myocardial Infarction (STEMI) is rising and the existing emergency medical aid system for STEMI was not enough for timely perfusion treatment. No existing research with high-quality data focuses on the characteristic of STEMI incidence and regional network construction. Aiming of Guangdong GAMI(reGional network for Acute Myocardial Infarction) project is to establish effective collaborative regional network system for STEMI patients treatment.
The project of Guangdong GAMI(reGional network for Acute Myocardial Infarction) is being conducted during 2015-2019 in eight districts with diverse economic development across southern China (Integrated care model was conducted in four regions, which mainly included community public education, non primary-PCI capable centre and referral system improvement, and inhospital green-channal optimization for primary-PCI capable centre. Other four centers were underwent usual care of acute myocardial infacrtion public and medical health service). All the ST-segment elevation myocardial infarction (STEMI) patients admitted in the hospital within 30 days from the symptom onset were enrolled. The key data of the timeline of STEMI onset and treatment were precisely recorded. Other details of STEMI treatment in hospitals such as laboratory data and medication were also collected. During the research period, actions of both optimizing the regional STEMI patients transfer and treatment to shorten the medical delay, as well as educating the public to improve their awareness of early treatment of STEMI were taken meanwhile. In addition, laboratory data, medication, and follow-up information were recorded in a database for further analysis regarding the STEMI patient treatment.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Enrollment
7,102
Publication education includes multiple methods of acute myocardial infarction knowledge education. Network construction includes regional connection of ST-Segment Elevation Myocardial Infarction patients transfer for percutaneous coronary intervention treatment, as well as physicians skill improvement in primary hospital.
Longyan First Hospital Affiliated to Fujian Medical University
Longyan, Fujian, China
Dongguan People's Hospital
Dongguan, Guangdong, China
Shunde Hospital of Southern Medical University
Foshan, Guangdong, China
Guangdong Provincial People's Hospital
Guangzhou, Guangdong, China
Receipt of reperfusion therapy within 12 hoursInfarction patients
The primary outcome was the proportion of patients who received symptom-to-reperfusion treatment within 12 hours.
Time frame: From 1 month before hospitalization to 24 hours after hospitalization
Onset-to-admission time within 12 hours
The proportion of patients who take a symptom-to-admission period within 12 hours.
Time frame: From 1 month before hospitalization to 24 hours after hospitalization
Door-to-balloon time within 90 minutes
The proportion of patients who take a door-to-balloon period within 90 minutes.
Time frame: 24 hours
In-hospital clinical outcomes
The incidence of several in-hospital outcomes (in-hospital death; and major adverse cardiac events \[MACEs\], which mainly included in-hospital death, recurrence of myocardial infarction, and stroke); the length of stay.
Time frame: 30 days
1-year all-cause mortality
Total mortality between 30 days and 1 year after discharge.
Time frame: 1 year
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