The purpose of this clinical research project is to explore potential biomarkers and validate the predictive and prognostic value of molecular signature in colorectal cancer.
This is a prospective observational study. Tumor tissue specimens and surgical specimens are obtained from the Sixth Affiliated Hospital, Sun Yat-sen University. The samples are analyzed for biomarkers. The biomarkers are correlated with clinical outcomes (failure-free survival, overall survival, tumor response to treatment (e.g. tumor regression grade for rectal cancer), distant metastasis, recurrence and death). The aim of the analysis is to explore potential biomarkers and validate the predictive and prognostic value of molecular signature in . This will lead to the definition of risk groups and stratification of patients and will help to precision medicine of colorectal cancer.
Study Type
OBSERVATIONAL
Enrollment
1,050
The Sixth Affiliated Hospital, Sun Yet-sen University
Guangzhou, China
RECRUITINGFailure-free Survival
Time frame: 3 years
Tumor regression grade
For rectal cancer patients who receive neoadjuvant treatment
Time frame: 1 year
Overall survival
Time frame: 3 years
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