Functional Imaging in the Acute Phase of Transient Ischemic Attacks

Centre Hospitalier Universitaire de Besancon70 enrolled

Overview

The aim of the study is to find a radiological biomarker of Transient Ischemic Attacks (TIA) thanks to functional Magnetic Resonance Imaging (fMRI) done within the 24 hour after symptoms onset.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

SINGLE

Enrollment

Conditions

Transient Ischemic Attack

Interventions

Functional Magnetic Resonance ImagingDIAGNOSTIC_TEST

fMRI sequences done with motor paradigm (right and left arm), followed by resting state acquisition

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patient admitted in for a transient neurologic deficit and suspicion of TIA of carotid circulation * Prescription for conventionnal MRI Exclusion Criteria: * Contraindication to MRI * Previous neurological disease (with lesions) * Severe psychiatric disease

Locations (1)

CHU de Besançon

Besançon, France

RECRUITING

Outcomes

Primary Outcomes

Blood-Oxygen-Level Dependent signal

BOLD effect differences in motor cortex from pathological side versus healthy side measured by fMRI within the 24 hours after symptom onset, during a motor paradigm

Time frame: 24 hours after symptoms onset

Secondary Outcomes

Resting state

Bold effect differences in resting state networks from pathological side versus healthy side measured by fMRI within the 24 hours after symptom onset, during a motor paradigm

Time frame: 24 hours after symptoms onset

Central Contacts

Louise BONNET, MD

CONTACT

033381668984 l1bonnet@chu-besancon.fr

Guillaume CHARBONNIER, MD

CONTACT

g1charbonnier@chu-besancon.fr

Data from ClinicalTrials.gov

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