Patients aged 65 or older under gastrointestinal surgery will be enrolled,the investigators will assess the frailty of these patients by Frailty Index Scale and explore the correlation between the frailty and perioperative adverse events.
Patients will be assessed by specially trained doctors or nurses after admission, including daily living ability, physiological function, social-psychological status, comorbidities, mental state, grip strength, walking speed. After the assessment, the patients' frailty index was obtained. Moreover, the operation time, intraoperative bleeding loss, perioperative complications, length of stay, hospitalization expenses, readmission rate within 30 days, mortality within 30 days and other outcome indicators of these patients will be recorded. The Main purposes of present study are to verify the feasibility of applying Frailty Index (FI) to assess the degree of frailty in elderly patients undergoing gastrointestinal surgery, compare the difference of perioperative adverse events in elderly patients with different degrees of frailty,find potential indicators for evaluating and predicting the safety of surgery in elderly patients, and provide reference data for the determination of future assessment tools of frailty. The secondary objective is to compare the quality of life and long-term prognosis(only for patients with cancers,including recurrence free survival and overall survival) of elderly patients with different degrees of frailty after gastrointestinal surgery.
Study Type
OBSERVATIONAL
Enrollment
500
We will evaluate the frailty with a Frailty Index Scale in elderly patients undergoing gastrointestinal surgery.
West China Hospital, Sichuan University
Chengdu, Sichuan, China
operative time
From the beginning of the skin incision to the end of the last incision was From the beginning of the skin incision to the end of the suture of last incision
Time frame: 2 year
Blood loss
intraoperative blood loss
Time frame: 2 year
Intraoperative complications
Including all the complications in the procedure
Time frame: 2 year
postoperative complications
including incision infection,anastomotic leakage,respiratory infection, postoperative bleeding and so on.
Time frame: 2 year
The length of stay in intensive care unit (ICU)
Time form entry to ICU to return to general ward after the condition is stable.
Time frame: 2 year
The length of hospitalization
Time from admission to discharge
Time frame: 2 year
Hospital costs
Cost of diagnosis and treatment during hospitalization
Time frame: 2 year
Readmission rate within 30 days
The proportion of patients who are re-hospitalized for postoperative complications after 30 days of discharge in all subjects.
Time frame: 2 year
Mortality within 30 days
death rate within 30 days after surgery in all patients after operation
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Time frame: 2 year
Recurrence-free Survival (RFS)
RFS is the abbreviation of recurrence-free survival, which refers to the duration from postoperation to tumor recurrence (Only for patients with cancers).
Time frame: 2 year
Overall survival (OS)
OS is the abbreviation of overall survival , which refers to the duration from postoperation to death of the subjects (Only for patients with cancers).
Time frame: 2 year