LODS score for deceased ICU patients within 30 days is higher than survived ICU patients
Study Type
OBSERVATIONAL
Enrollment
439
Variables of logistic organ dysfunction system score, including: GCS; heart rate; systolic BP; blood urea; serum creatinine; urine output; leucocyte count; platelet count; PaO2/FiO2; serum bilirubin; prothrombin time.
Rumah Sakit Cipto Mangunkusumo
Jakarta Pusat, DKI Jakarta, Indonesia
LODS score discrimination ability
LODS score ability to discriminate patient outcomes based on variables of logistic organ dysfunction system scores: GCS; heart rate; systolic BP; blood urea; serum creatinine; urine output; leucocyte count; platelet count; PaO2/FiO2; serum bilirubin; prothrombin time.
Time frame: 30 days from admission
LODS score calibration
LODS score ability to predict patient outcomes based on variables of logistic organ dysfunction system scores: GCS; heart rate; systolic BP; blood urea; serum creatinine; urine output; leucocyte count; platelet count; PaO2/FiO2; serum bilirubin; prothrombin time.
Time frame: 30 days from admission
Correlation between LODS score variables with patient outcome
Correlation between patient outcomes with each LODS score variables: GCS; heart rate; systolic BP; blood urea; serum creatinine; urine output; leucocyte count; platelet count; PaO2/FiO2; serum bilirubin; prothrombin time.
Time frame: 30 days from admission
Patient outcome
Patient outcome within 30 days of admission to intensive care unit (ICU): deceased or survived
Time frame: 30 days from admission
LODS neurologic variable score: Glasgow Coma Scale (GCS)
The score for GCS variable cutoff: 0 point for 14-15; 1 point for 9-13; 3 points for 6-8; 5 points for 3-5.
Time frame: Day 1
LODS cardiovascular variable score: Heart rate (HR) and/or systolic blood pressure (SBP)
The score for HR (in bpm) and/or SBP (in mmHg) variable cutoff: 0 point for HR 30-139 and SBP 90-239; 1 point for SBP 70-89 or 240-269 or HR \>=140; 3 points for SBP 40-69 or \>=270; 5 points for HR \<30 or SBP \<40.
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Time frame: Day 1
LODS renal variable score: serum urea nitrogen (BUN) and/or creatinine and/or urine output (UO)
The score for BUN (in mg/dL) and/or creatinine (in mg/dL) and/or UO (in litres/day) variable cutoff: 0 point for BUN \<17 AND creatinine \<1.20 AND UO 0.75-9.99; 1 point for BUN 17-\<28 OR creatinine 1.20-1.59; 3 points for BUN 28-\<56 AND creatinine \<1.60 AND UO 0.5-0.74 or \>=10; 5 points for BUN \>=56 OR UO 0.5.
Time frame: Day 1
LODS pulmonary variable score: Partial oxygen pressure (PaO2)/Fraction of inspired oxygen (FiO2) on Mechanical Ventilation (MV) or Continuous Positive Airway Pressure (CPAP)
The score for PaO2/FiO2 (in mmHg/%) variable cutoff: 0 point for no ventilation and no CPAP; 1 point for \>=150; 3 points for \<150.
Time frame: Day 1
LODS hematologic variable score: white blood cell (WBC) count and/or platelet count
The score for WBC (in x10\^3/L) and/or platelet count in (x10\^3/L) variable cutoff: 0 point for WBC 2.5-49.9 and platelet \>=50; 1 point for WBC 1.0-2.4 or \>=50.0 OR platelet \<50; 3 points for WBC \<1.0
Time frame: Day 1
LODS hepatic function variable score: Serum Bilirubin and/or Prothrombin time (PT)
The score for serum bilirubin (in mg/dL) and/or PT (in % of standard) variable cutoff: 0 point for bilirubin \<2.0 and PT \>=25; 1 point for bilirubin \>=2.0 OR PT\<25% or \>3.
Time frame: Day 1