Association Between a Peri-traumatic Dissociation State and the Occurrence of Post-traumatic Stress Syndrome

University Hospital, Brest148 enrolled

Overview

Patients will be selected after studying clinical records.Patients who had general anesthesia due to an injury related to severe trauma within 6 to 12 months prior to inclusion will be included. Three self-survey will be completed by the patient: PDEQ, PCL-5 and a demographic questionnaire. According to the PDEQ and PCL-5 scores, an association between a peri-traumatic dissociation state and a post-traumatic stress disorder can be established.

Study Type

INTERVENTIONAL

Allocation

Purpose

PREVENTION

Masking

NONE

Enrollment

148

Conditions

Severe Trauma General Anaesthesia

Interventions

PDEQ, PCL-5 and demographic surveyDIAGNOSTIC_TEST

Questionnaires

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with general anesthesia for a surgical wound with violent trauma in the road, a fall of more than 6 meters, burn, accident at work, explosion, aggression) in the 6 to 12 months before the inclusion * Time between trauma and general anesthesia should not exceed 48 hours * Patient agreeing to participate in the study. Exclusion Criteria: * Minor patients * Patients under curatorship, and tutorship * Patient deprived of liberty * Patients who do not speak French * Patients who are not in satisfactory neurological state to answer the questionnaire (pyschotic, demented states) * Patients who have been sedated (apart from general anesthesia) when receiving or having a Glasgow score \<14

Locations (1)

CHRU Brest

Brest, France

Outcomes

Primary Outcomes

Studying association between the presence of peri-traumatic dissociation state and the achievement of post-traumatic stress disorder between 6 and 12 months in traumatized patients

Association will be measured using PDEQ scale and PCL-5 scale. The peri-traumatic dissociation will be evaluated by the Peri-traumatique Dissociation Experience Questionnary (PDEQ scale). This questionnaire contains ten items to study the presence or not of a peri-traumatic dissociation state. The items are scored on a 5-point Likert scale ranging from 1 (not at all true) to 5 (extremely true). The total score is the sum of all the items. A score from 15 indicates a significant dissociation. The presence or not of a Post-Traumatic Stress Disorder (PTSD) will be evaluated by the Post-Traumatic Stress Disorder Checklist Scale-Version DSM 5 (PCL-5). This questionnaire contains twenty items to study the presence or not of a PTSD. A total score for symptom severity (0-80) can be obtained by summing the scores for each of the 20 items. A score over 31 indicates a PTSD.

Time frame: study baseline (6 to 12 months after initial hospitalisation)

Secondary Outcomes

Measurement of the frequency of PTSD after severe trauma requiring general anesthesia.

Time frame: study baseline (6 to 12 months after initial hospitalisation)

Research of Risk Factors Associated with the Occurrence of PTSD

Time frame: study baseline (6 to 12 months after initial hospitalisation)

Data from ClinicalTrials.gov

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