In this study, the prevalence of metabolic syndrome in psoriatic and psoriatic arthritis patients as well as the parameters of metabolic syndrome will be examined. At the same time, the levels of omentin and visfatin adipokines associated with metabolic syndrome and obesity will be measured by measuring the disease severity (by PASI psoriasis, clinical activity score for psoriatic arthritis). The patients who accepted to participate in the study , who were admitted to the dermatology outpatient clinic were included in the study. For the blood tests required after the examination, 2 tubes of blood will be taken for the measurement of omentin and visfatin. 80 psoriasis, 40 psoriatic arthritis and 60 healthy volunteers were planned to be studied. AHA / NHLBI, 2005 (revised ATP III criteria) criterion for the diagnosis of metabolic syndrome will be used. Omentin and visfatin levels are compared with the severity of the disease for psoriasis and psoriatic arthritis, and it will be examined whether it is proinflammatory or antiinflammatory.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
SINGLE
Enrollment
180
diagnostic blood test
Istanbul Medeniyet University, Department of dermatology
Istanbul, Turkey (Türkiye)
Istanbul Medeniyet University
Istanbul, Turkey (Türkiye)
omentin
Omentin (omentin 1-2) is a specific protein that consists of amino acids released from vascular vessels
Time frame: 6 months
visfatin
Visfatin is an insulin-like protein that binds to insulin receptors produced mostly from visceral fatty tissue.
Time frame: 6 months
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