Autoimmune thyroid disease (AITD) is the main cause of hypothyroidism in reproduction women, iodine and bisphenol A are the environmental factors for AITD. The research was mainly designed to investigate the effect of iodine and BPA on AITD in reproduction women to provide new evidence for hypothyroidism in reproduction women.
71 patients with thyroid autoantibody positive were treated as AITD group, another 71 healthy reproduction women were selected as normal group. Women age, BMI, thyroid disease history, family history, marital and reproductive history, whether the application of iodized salt, thyroid function and thyroid autoantibodies detection were recorded. Meanwhile urine iodine, urinary iodine/urinary creatinine, urine BPA and urinary BPA/creatinine were tested. The urine iodine and BPA levels of the two groups were compared. Taking AITD as the dependent variable, logistic regression was conducted to analyze whether urinary iodine and BPA were risk factors of AITD.
Study Type
OBSERVATIONAL
Enrollment
142
urinary iodine and urine BPA
Peking University international hospital
Beijing, Beijing Municipality, China
RECRUITINGComparison of urinary iodine levels between the two groups
Urinary iodine levels were compared between patients with autoimmune thyroid disease and normal women.
Time frame: 2019-2011
Comparison of urinary BPA levels between the two groups
Urinary BPA levels were compared between patients with autoimmune thyroid disease and normal women.
Time frame: 2019-2011
Influencing factors of autoimmune thyroid diseases.
Abnormal levels of iodine and PBA are influential factors in autoimmune thyroid disease.
Time frame: 2019-2012
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