Correlation Between Muscle Thickness and Inflammation With Ventilator Use in Critically Ill Patients

Indonesia University52 enrolled

Overview

Decrease thickness of diaphragm muscle, cross-sectional area of rectus femoris and biceps brachii muscle, and increase in CRP would affect ventilator length of use in critically ill patients in ICU

Study Type

OBSERVATIONAL

Enrollment

Conditions

Ventilation Therapy; Complications

Interventions

Diaphragm thicknessOTHER

measured at apposition zone using ultrasonography in mm

Cross-sectional area of rectus femoris muscleOTHER

measured at lower one-third line between Spina iliaca anterior inferior (SIAI) and upper border femur patella using ultrasonography in cm\^2

Cross-sectional area of biceps brachiiOTHER

measured at biceps brachii muscle using ultrasonography in cm\^2

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients who had Modified Rankin Score \< 4 in 1 month before admitted into ICU Exclusion Criteria: * Pregnant women * Patients who had intubation more than 24 hours before admitted at ICU Cipto Mangunkusumo Hospital * Patients who had a history or prior to thoracic or heart surgery 14 days before admission * Patients who had severe peripheral muscle dysfunction * Patients who had a history of admission in hospital for more than 2 weeks on the last 3 months * Patients who predicted will be using ventilator for less than 4 days * Patients who suffered acute respiratory distress syndrome (ARDS) with a ratio of arterial oxygen partial pressure to fractional inspired oxygen (PaO2/FiO2) less than 200 * Patients who declined to participate in this study

Locations (1)

Rumah Sakit Cipto Mangunkusumo

Jakarta Pusat, DKI Jakarta, Indonesia

Outcomes

Primary Outcomes

Correlation between changes in diaphragm thickness with ventilator length of use

Correlation between changes in diaphragm thickness with ventilator length of use: \< 7 days or \>7 days