Measurement of Cardiac Output in Intensive Care Unit With Unstable Hemodynamic: Validation of Physioflow® Device Versus Trans Thoracic Echocardiography

Centre Hospitalier Universitaire, Amiens1 enrolled

Overview

Physioflow® is a new device for measuring cardiac output in a non-invasive way using a thoracic bioimpedance technique. This technique has been validated in patients in stress tests as well as in Chronic Obstructive Pulmonary Disease (COPD) patients, in obese patients and in children. Very little work has been published in intensive care unit (ICU) and no studies have been done on hemodynamically unstable patients. The aim of this work is to compare the cardiac output measured by Physioflow® to the transthoracic echocardiography (TTE) in ventilated, sedated patients hospitalized in ICU receiving catecholamines and for whom the attending physician wants to evaluate the fluid responsiveness using the TTE and a passive leg raising maneuver (PLR).

All patients included will be simultaneously monitored with TTE and the Physioflow® thoracic electrical bioimpedance device. Cardiac output is measured by the Physioflow® Thoracic Bioimpedance Device and TTE before and after PLR. If the attending physician decide to administer fluid expansion a new set of cardiac output measurement will be performed before and after the volume expansion.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Cardiac Output

Interventions

cardiac output measure with TTE

cardiac output measure with Physioflow® thoracic electrical bioimpedancePROCEDURE

All patients included will be simultaneously monitored with transthoracic echocardiography (TTE) and the Physioflow® thoracic electrical bioimpedance device. Cardiac output is measured by the Physioflow® Thoracic Bioimpedance Device and TTE before and after passive leg raising maneuver (PLR)

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patient more than 18 year-old * patient sedated and adapted to the assisted controlled ventilation * patient receiving catecholamine (norepinephrine, epinephrine or dobutamine) * patient requiring an haemodynamic evaluation by trans-thoracic echocardiography and PLR according to the attending physician Exclusion Criteria: * pregnant women * patients with a poor echogenicity * patients deprived of public law

Outcomes

Primary Outcomes

Measure of cardiac output with transthoracic echocardiography (TTE) before PLR

Measure of Cardiac output with transthoracic echocardiography (TTE) before passive leg raising maneuver (PLR)