Pharmacokinetics Centella Asiatica Product (CAP) in Mild Cognitive Impairment

Inclusion Criteria: 1. Age 65-85, male and female 2. Meet the National Institute of Aging - Alzheimer's Association core clinical criteria for mild cognitive impairment or probable Alzheimer's disease dementia with a Clinical Dementia Rating (CDR) score of 0.5-1 and MMSE score of 20-28 3. Report a history of subjective memory decline with gradual onset and slow progression over the last one year before screening; MUST be corroborated by an informant 4. On cholinesterase inhibitor therapy for Alzheimer's disease (AD) and must be on a stable dose for at least 12 weeks prior to baseline 5. Caregiver/study partner that can accompany participant to all study visits 6. Sufficient English language skills to complete all tests 7. Sufficient vision and hearing to complete all tests 8. No known allergies to Centella asiatica or CAP excipients 9. Willingness to discontinue all botanical dietary supplements for one week prior to and during each study visit 10. Willingness to comply with a 48-hour low plant diet for each study visit 11. Absence of significant depression symptoms (Geriatric Depression Scale-15 score of \<12) 12. Body Mass Index (BMI) greater than 17 and less than 35 at screening 13. General health status that will not interfere with the ability to complete the study Exclusion Criteria: 1. Current smoking, alcohol or substance abuse according to DSM-V criteria 2. Women who are pregnant, planning to become pregnant or breastfeeding 3. Men who are actively trying to conceive a child or planning to within three months of study completion 4. Severe aversion to venipuncture 5. Abnormal laboratory evaluation indicating asymptomatic and untreated urinary tract infection 6. Cancer within the last five years, with the exception of localized prostate cancer (Gleason Grade \<3) and non-metastatic skin cancers 7. Comorbid conditions such as diabetes mellitus, kidney failure, liver failure, hepatitis, blood disorders, clinical symptomatic orthostatic hypotension, and unstable or significantly symptomatic cardiovascular disease 8. Significant disease of the central nervous system such as brain tumor, seizure disorder, subdural hematoma, cranial arteritis, or clinically significant stroke 9. Major depression, schizophrenia, or other major psychiatric disorder defined by DSM-V criteria 10. Medications: sedatives (except those used occasionally for sleep), central nervous system active medications that have not been stable for two months (including beta blockers, cimetidine, SSRIs, SNRIs), anticoagulants (i.e. Warfarin), investigational drugs used within five half-lives of baseline visit, systemic corticosteroids, neuroleptics, anti-Parkinsonian agents, narcotic analgesics, nicotine (tobacco, patches, gum, lozenges, etc.), Cannabis sativa (herb or edibles) 11. Non-Alzheimer dementia such as vascular dementia, normal pressure hydrocephalus or Parkinson's disease 12. Mini Mental State Examination (MMSE) score of \<20 or \>28 or CDR score \>1 or zero 13. Unwilling to maintain stable dosage of AD medications throughout study duration 14. Inability or unwillingness of individual or legal guardian/representative to give written informed consent. 15. Current drug or alcohol use or dependence that, in the opinion of the site investigator, would interfere with adherence to study requirements.