Intraocular Pressure and Optic Nerve Sheath Diameter Changes at Different PEEP Levels

Marmara University15 enrolled

Overview

Positive end-expiratory pressure (PEEP) is sometimes used during perioperative period, as it has favourable effects on lung mechanics. Unfortunately, it has some negative effects on the patients, like increased intraabdominal, intrathoracic, intracranial and intraocular pressures. In this study the investigators aimed to investigate the effects of different PEEP levels on the patients' intraocular and intracranial pressures. Intraocular pressure will be measured by ocular tonometry, and intracranial pressure will be estimated by optic nerve sheath diameter measurement. The measurements will be performed in the operating room in the patients undergoing laparotomic surgery.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

DIAGNOSTIC

Masking

SINGLE

Enrollment

Conditions

Intraocular Pressure Intracranial Pressure Positive End-expiratory Pressure

Interventions

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients undergoing laparotomy for gastrointestinal surgery * American Society of Anesthesiologists (ASA) 1 or 2 physical status * Elective surgery Exclusion Criteria: * Patients with glaucoma * ASA 3 or over physical status * Emergency surgery

Outcomes

Primary Outcomes

Changes in intraocular pressure

The physiological value for intraocular pressure is 10-20 mm Hg. Changes in intraocular pressure will be observed throughout the surgery, as will its relationship with the positive end-expiratory pressure application.

Time frame: Throughout the operation (usually about 1.5 hours).

Changes in optic nerve sheath diameter

Changes in optic nerve sheath diameter will be observed throughout the surgery, as will its relationship with the positive end-expiratory pressure application.