This study is a controlled pilot study with 17 participants with Multiple Sclerosis (MS). The primary goal of this study is to objectively examine the effects of a multimodal dance intervention on walking-related performance fatigability. The secondary aim is to investigate the effects of a multimodal dance intervention on other MS symptoms related to fatigue and fatigability. The following research questions will be addressed: 1. Does a multimodal dance intervention have positive effects on walking-related fatigability? 2. Does a multimodal dance intervention have positive effects on other MS symptoms related to fatigue and fatigability?
This study distinguish two groups contributing to a dance and art production. The experimental group will perform 10 weeks of dance training, while the other group will contribute to the production in various ways (e.g. word art, photography, painting, …). Measures will be taken before and after the training or assistance in the production.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
17
Hasselt University
Hasselt, Belgium
motor fatigability
Performance motor fatigability: Calculating the Distance Walked Index (DWI) during 6MWT. Formula for walking-related performance fatigability: DWI = (\[Distance walked at minute 6 - Distance walked at minute 1\]/Distance walked at minute 1) × 100
Time frame: Baseline
motor fatigability
Performance motor fatigability: Calculating the Distance Walked Index (DWI) during 6MWT. Formula for walking-related performance fatigability: DWI = (\[Distance walked at minute 6 - Distance walked at minute 1\]/Distance walked at minute 1) × 100
Time frame: week 10
motor fatigability
Performance motor fatigability: Calculating the Distance Walked Index (DWI) during 6MWT. Formula for walking-related performance fatigability: DWI = (\[Distance walked at minute 6 - Distance walked at minute 1\]/Distance walked at minute 1) × 100
Time frame: week 20
Trait motor fatigue
Modified Fatigue Impact Scale (MFIS)
Time frame: baseline
Trait motor fatigue
Modified Fatigue Impact Scale (MFIS)
Time frame: week 10
Trait motor fatigue
Modified Fatigue Impact Scale (MFIS)
Time frame: week 20
Coördination test with lower limbs
seated bipedal coordination task (knee flexion and extension movements during 6 minutes, and metronome based 0,75 Hz, 1Hz and 1,5 Hz for 1 minute)
Time frame: baseline
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Coördination test with lower limbs
seated bipedal coordination task (knee flexion and extension movements during 6 minutes, and metronome based 0,75 Hz, 1Hz and 1,5 Hz for 1 minute)
Time frame: week 10
Coördination test with lower limbs
seated bipedal coordination task (knee flexion and extension movements during 6 minutes, and metronome based 0,75 Hz, 1Hz and 1,5 Hz for 1 minute)
Time frame: week 20
Perceived motor fatigability
VAS increase minute per minute during 6MWT (range 0-10)
Time frame: Baseline
Perceived motor fatigability
VAS increase minute per minute during 6MWT (range 0-10)
Time frame: week 10
Perceived motor fatigability
VAS increase minute per minute during 6MWT (range 0-10)
Time frame: week 20
Performance cognitive fatigability and cognitive capacity
PASAT and SDMT total score and correct answers last ⅓ vs first ⅓
Time frame: Baseline
Performance cognitive fatigability and cognitive capacity
PASAT and SDMT total score and correct answers last ⅓ vs first ⅓
Time frame: week 10
Performance cognitive fatigability and cognitive capacity
PASAT and SDMT total score and correct answers last ⅓ vs first ⅓
Time frame: week 20
Trait fatigue
Fatigue Severity Scale (FSS) : range 1-7
Time frame: Baseline
Trait fatigue
Fatigue Severity Scale (FSS) : range 1-7
Time frame: week 10
Trait fatigue
Fatigue Severity Scale (FSS) : range 1-7
Time frame: week 20
MSIS-29 Questionnaire
Impact of MS via a questionnaire. 29 items, total score on 145.
Time frame: Baseline
MSIS-29 Questionnaire
Impact of MS via a questionnaire. 29 items, total score on 145.
Time frame: week 10
MSIS-29 Questionnaire
Impact of MS via a questionnaire. 29 items, total score on 145.
Time frame: week 20
SF-36 Questionnaire
Quality of Life health related questionnaire. Scale 0-100
Time frame: Baseline
SF-36 Questionnaire
Quality of Life health related questionnaire. Scale 0-100
Time frame: week 10
SF-36 Questionnaire
Quality of Life health related questionnaire. Scale 0-100
Time frame: week 20
ABC scale
Activity balance confidence scale. Scale has 16 items and is transferred to a percentage.
Time frame: Baseline
ABC scale
Activity balance confidence scale. Scale has 16 items and is transferred to a percentage.
Time frame: week 10
ABC scale
Activity balance confidence scale. Scale has 16 items and is transferred to a percentage.
Time frame: week 20
MSWS-12 Questionnaire
Questionnaire about walking in MS, 12 items, total score on 60, minimum score 12.
Time frame: Baseline
MSWS-12 Questionnaire
Questionnaire about walking in MS, 12 items, total score on 60, minimum score 12.
Time frame: week 10
MSWS-12 Questionnaire
Questionnaire about walking in MS, 12 items, total score on 60, minimum score 12.
Time frame: week 20
5xSTS T25FW
5 times sit to stand test, where patients have to stand and sit 5 times as fast as possible. Determined in seconds
Time frame: Baseline
5xSTS T25FW
5 times sit to stand test, where patients have to stand and sit 5 times as fast as possible. Determined in seconds
Time frame: week 10
5xSTS T25FW
5 times sit to stand test, where patients have to stand and sit 5 times as fast as possible. Determined in seconds
Time frame: week 20
T25FW test
patients have to walk 25 feet as fast as possible. Determined in seconds
Time frame: Baseline
T25FW test
patients have to walk 25 feet as fast as possible. Determined in seconds
Time frame: week 10
T25FW test
patients have to walk 25 feet as fast as possible. Determined in seconds
Time frame: week 20
NHPT (Nine hole peck test)
Nine hole peck test: descriptive measure for hand dexterity. Measured in seconds.
Time frame: Baseline
NHPT (Nine hole peck test)
Nine hole peck test: descriptive measure for hand dexterity. Measured in seconds.
Time frame: week 10
NHPT (Nine hole peck test)
Nine hole peck test: descriptive measure for hand dexterity. Measured in seconds.
Time frame: week 20
DGI (Dynamic gait index)
patient have to perform several static and dynamic balance test. A four-point ordinal scale, ranging from 0-3. "0" indicates the lowest level of function and "3" the highest level of function. Total Score = 24
Time frame: Baseline
DGI (Dynamic gait index)
patient have to perform several static and dynamic balance test. A four-point ordinal scale, ranging from 0-3. "0" indicates the lowest level of function and "3" the highest level of function. Total Score = 24
Time frame: week 10
DGI (Dynamic gait index)
patient have to perform several static and dynamic balance test. A four-point ordinal scale, ranging from 0-3. "0" indicates the lowest level of function and "3" the highest level of function. Total Score = 24
Time frame: week 20
EmNSA
Dynamic gait index: patient have to perform several static and dynamic balance test. A ordinal scale, ranging from 0-2. "0" indicates the lowest level of function and "2" the highest level of function. Total Score = 48
Time frame: Baseline
EmNSA
Dynamic gait index: patient have to perform several static and dynamic balance test. A ordinal scale, ranging from 0-2. "0" indicates the lowest level of function and "2" the highest level of function. Total Score = 48
Time frame: week 10
EmNSA
Dynamic gait index: patient have to perform several static and dynamic balance test. A ordinal scale, ranging from 0-2. "0" indicates the lowest level of function and "2" the highest level of function. Total Score = 48
Time frame: week 20
CMI (Cognitive motor interference)
Dual task testing during 1 min tasks and 6 minutes task to measure alertness of movement control. Dual task testing during 1 min tasks and 6 minutes task to measure alertness of movement control.
Time frame: Baseline
CMI (Cognitive motor interference)
Dual task testing during 1 min tasks and 6 minutes task to measure alertness of movement control. Dual task testing during 1 min tasks and 6 minutes task to measure alertness of movement control.
Time frame: week 10
CMI (Cognitive motor interference)
Dual task testing during 1 min tasks and 6 minutes task to measure alertness of movement control. Dual task testing during 1 min tasks and 6 minutes task to measure alertness of movement control.
Time frame: week 20