True-false-true occurred during wire penetration in coronary CTO procedure. Subintimal stenting influences vascular response. Intravenous ultrasound confirmed wire position in the procedure. Then stenting procedure was performed. Optical coherence tomography was used for exploring long-term vascular response and healing profile after successful coronary stenting in CTO lesions.
Chronic total occlusions (CTOs) are defined as coronary lesions with thrombolysis in myocardial infarction (TIMI) grade flow of 0 and present for more than 3 months. CTO is commonly recognized as the toughest lesion subset to be treated by percutaneous coronary interventions. With the remarkable progress in the technologies and techniques achieved in the PCI for CTO over the last decade, the rate of procedural success increased to 80-90%. Chronic total occlusion is associated with a higher incidence of malapposition and uncovered stent struts. At present, four strategies were used for CTO lesions, including: ante-grade wire escalation, ante-grade dissection reentry (ADR), retro-grade wire escalation, and retrograde dissection reentry (RDR). True-false-true occurred during wire penetration. Subintimal stenting influences vascular response. Intravenous ultrasound (IVUS) confirmed wire position in the procedure. Then stenting procedure was performed according to standard routine. Optical coherence tomography (OCT) was used for exploring long-term vascular response and healing profile after successful coronary stenting in CTO lesions.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
60
Patients with coronary chronic total occlusion received successful stenting. Optimal coherence tomography imaged immediately and at 9-12 months after the index procedure to explore long-term vascular response and healing profile.
Zhongshan Hospital, Fudan University
Shanghai, Shanghai Municipality, China
RECRUITINGlong-term minimal stent area
measured through OCT imaging result
Time frame: 9-12 month after index procedure
long-term stent thrombosis
measured through OCT imaging result
Time frame: 9-12 month after index procedure
long-term stent neointima
measured through OCT imaging result
Time frame: 9-12 month after index procedure
long-term stent malapposition
measured through OCT imaging result
Time frame: 9-12 month after index procedure
immediately minimal stent area
measured through OCT imaging result
Time frame: in the procedure
immediately stent malapposition
measured through OCT imaging result
Time frame: in the procedure
Major Adverse Cardiovascular Events
clinical follow-up record
Time frame: 9-12 month after index procedure
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